Course Details

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Course Information
SemesterCourse Unit CodeCourse Unit TitleT+P+LCreditNumber of ECTS CreditsLast Updated Date
5MBG465MOLECULAR ENDOCRINOLOGY3+0+03523.05.2026

 
Course Details
Language of Instruction English
Level of Course Unit Bachelor's Degree
Department / Program MOLECULAR BIOLOGY AND GENETICS
Type of Program Formal Education
Type of Course Unit Elective
Course Delivery Method Face To Face
Objectives of the Course 1. Exploring the molecular mechanisms of hormone synthesis, secretion, and action in animal and human systems.
2. Integrating cellular signaling pathways with physiological regulation of growth, metabolism, reproduction, and stress responses.
3. Developing a critical understanding of how endocrine signaling networks are investigated through molecular and biochemical research approaches, and how these models inform translational and drug-target studies.
Course Content This course explores the molecular foundations of hormone action, emphasizing how endocrine signals regulate cellular function, gene expression, and organismal homeostasis. Students examine hormone biosynthesis, secretion, and receptor-mediated signal transduction through selected examples such as pancreatic, thyroid, adrenal, and adipose systems. Integrating experimental and clinical perspectives, the course highlights how disruption of hormonal pathways contributes to disease and how these mechanisms inspire molecular and pharmacological research on endocrine targets.
Course Methods and Techniques Lectures, Interactive Discussions, Multimedia Presentations, Readings and Literature Review, Quizzes and Exams
Prerequisites and co-requisities None
Course Coordinator None
Name of Lecturers Asist Prof.Dr. Berrak Yetimler https://avesis.agu.edu.tr/berrak.yetimler berrak.yetimler@agu.edu.tr
Assistants None
Work Placement(s) No

Recommended or Required Reading
Resources The course sldies and the relevant textbook recommendations will be shared throughout the semester
Course Notes Weekly lecture slides, relevant scientific articles, and supporting visuals will be shared during class. All materials will be accessible on Canvas in the week following each session.
Documents Canvas
Assignments Canvas

Course Category
Engineering %10
Science %30
Health %40
Field %10

Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria
In-Term Studies Quantity Percentage
Quiz/Küçük Sınav 2 % 50
Final examination 1 % 50
Total
3
% 100

 
ECTS Allocated Based on Student Workload
Activities Quantity Duration Total Work Load
Tartışma 2 2 4
Yazılı Sınav 3 3 9
Sınıf İçi Aktivitesi 14 1 14
Sunum için Hazırlık 7 2 14
Teslim İçin Hazırlık 1 3 3
Sunum 7 2 14
Okuma 7 2 14
Tekrar Anlatım 1 3 3
Araştırma 7 2 14
Kişisel Çalışma 3 2 6
Seminer 1 1 1
Teslim 7 1 7
Yüz Yüze Ders 14 3 42
Final Sınavı 1 3 3
Total Work Load   Number of ECTS Credits 5 148

 
Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
NoLearning Outcomes
1 Define the biosynthesis, secretion, and regulation of major hormones at the molecular level.
2 Compare signaling mechanisms among hormone receptor families and downstream pathways.
3 Explain how alterations in hormonal signaling lead to selected endocrine disorders.
4 Critically assess scientific data on hormone action and regulation.
5 Relate endocrine mechanisms to potential molecular and pharmacological research applications.

 
Weekly Detailed Course Contents
WeekTopicsStudy MaterialsMaterials
1 Introduction to Endocrinology: endocrine systems, hormones, and homeostasis
2 Molecular basis of hormone synthesis, secretion, and transport
3 Hormone receptors and signal transduction pathways
4 Nuclear receptors and regulation of gene expression
5 Peptide hormones and GPCR-mediated signaling mechanisms
6 Steroid hormones and intracellular signaling pathways
7 Regulation of glucose metabolism: pancreatic hormones and metabolic control
8 Thyroid hormones and regulation of metabolism and development
9 Adrenal hormones, stress responses, and neuroendocrine regulation
10 Adipose tissue as an endocrine organ: leptin, adipokines, and energy balance
11 Reproductive endocrinology and hormonal regulation of development
12 Molecular mechanisms of endocrine disorders and endocrine-related diseases
13 Experimental approaches in endocrine research and analysis of scientific literature
14 Molecular pharmacology of endocrine targets, emerging therapies, and general course review

 
Contribution of Learning Outcomes to Programme Outcomes
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10
C1 3 5 4 4 2
C2 3 5 4 4
C3 3 5 4 4 2 1
C4 5 4 2 5 2 3 2 1 2
C5 4 2 2 3 5 5 2 1 2

  Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

  
  https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=79742&lang=en
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