Course Details

Course Information
SemesterCourse Unit CodeCourse Unit TitleT+P+LCreditNumber of ECTS CreditsLast Updated Date
1BENG555IMMUNOGLOBULIN G:PRODUCTION STRUCTURE AND FUNCTION3+0+037,514.05.2025

 
Course Details
Language of Instruction English
Level of Course Unit Master's Degree
Department / Program BIOENGINEERING
Type of Program Formal Education
Type of Course Unit Elective
Course Delivery Method Face To Face
Objectives of the Course Teaching basic concepts and pathways leading the production of IgG.
Identifying the importance of IgG.
Describing the complexity of IgG in terms of production, function and applications of IgG.
Underlining the importance of thinking in molecular level in science.
Course Content This course covers the topics for the production, structure and function of Immunoglobulin G as well as pathogenicity in autoimmune diseases and pharmaceutical applications of IgG. The course starts with interaction between T and B cell interactions leading to the production of IgG. Then, the relation between structure and function of IgG will be covered by focusing on the motifs of IgG connecting the adaptive and innate immunity for the protection of the host. The classes will finally focus on the importance and contribution of IgG to the autoimmune disease such as rheumatoid arthritis and applications of IgG as therapeutic and vaccine.
Course Methods and Techniques This course adopts a student-centered and research-based instructional approach. The theoretical content is delivered through instructor-led lectures and presentations, enriched with visual materials, three-dimensional structural models, and examples from current scientific literature. To promote active participation, the course incorporates interactive sessions, question-and-answer discussions, small group work, and guided in-class analysis. As topics such as the structure, production, and immunological functions of Immunoglobulin G (IgG) are covered, the use of concept maps and molecular structure simulations supports deeper understanding of complex immune mechanisms.

A problem-based learning strategy is employed to encourage students to work on case scenarios involving the role of IgG in immune responses and autoimmune conditions. In addition, case-based learning is used to analyze real clinical examples, such as rheumatoid arthritis, focusing on the pathogenic effects of IgG. To foster scientific thinking and improve literature analysis skills, students complete weekly reading assignments, present recent research articles, and participate in small group projects.

In the final part of the course, the pharmaceutical and therapeutic applications of IgG—such as monoclonal antibodies and vaccines—are explored through case studies and clinical research findings. This comprehensive approach aims to ensure that students not only acquire theoretical knowledge but also develop the ability to apply it in clinical and biotechnological contexts.
Prerequisites and co-requisities None
Course Coordinator None
Name of Lecturers Asist Prof.Dr. EMEL BAŞAK GENCER AKÇOK
Assistants None
Work Placement(s) No

Recommended or Required Reading
Resources Fundamental Immunology,William E. Paul, 8th Ed, Wolters Kluwer
The Antibodies, Maurizio Zanetti, Melvin Reichman, 2nd edition (2014), CRC Press
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Assignments canvas
Exams sınıf içi

Course Category
Science %100

Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria
In-Term Studies Quantity Percentage
Yarıyıl İçi Çalışmalarının Başarı Notunun Katkısı 1 % 30
Sunum/Seminer 1 % 30
Final examination 1 % 40
Total
3
% 100

 
ECTS Allocated Based on Student Workload
Activities Quantity Duration Total Work Load
Ev Ödevi 6 2 12
Sunum için Hazırlık 4 7 28
Sunum 4 1 4
Proje 1 10 10
Okuma 10 3 30
Kişisel Çalışma 7 3 21
Ders dışı çalışma 14 2 28
Yüz Yüze Ders 14 3 42
Final Sınavı 1 15 15
Total Work Load   Number of ECTS Credits 7,5 190

 
Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
NoLearning Outcomes
1 Describe basic concepts and pathways leading the production of IgG.
2 Define the structure-function relation in IgG.
3 Recognize the importance of IgG in bridging innate and adaptive arms of immune system.
4 Describe how IgG can contribute to autoimmune diseases
5 Explain how IgG molecules utilized as a therapeutic

 
Weekly Detailed Course Contents
WeekTopicsStudy MaterialsMaterials
1 Overview of immune system
2 Overview of immune system
3 İnnate and adaptive immunity
4 İnnate and adaptive immunity
5 İnnate and adaptive immunity
6 B and T cell interaction
7 B and T cell interaction
8 IgG production
9 IgG structure and function
10 IgG in health and diseases
11 IgG in health and diseases
12 IgG in health and diseases
13 IgG and therapy
14 IgG in health and diseases

 
Contribution of Learning Outcomes to Programme Outcomes
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10 P11 P12
C1 5 4 3 4 5 5 4 4 4 4 3 5
C2 5 4 3 4 5 5 4 4 4 4 3 5
C3 5 4 3 4 5 5 4 4 4 4 3 5
C4 5 4 3 4 5 5 4 4 4 4 3 5
C5 5 4 3 4 5 5 4 4 4 4 3 5

  Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

  
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