| Semester | Course Unit Code | Course Unit Title | T+P+L | Credit | Number of ECTS Credits | Last Updated Date |
| 4 | BENG552 | NATURAL PRODUCT DISCOVERY AND BIOSYNTHESIS | 3+0+0 | 3 | 7,5 | 14.05.2025 |
|
Language of Instruction
|
English
|
|
Level of Course Unit
|
Master's Degree
|
|
Department / Program
|
BIOENGINEERING
|
|
Type of Program
|
Formal Education
|
|
Type of Course Unit
|
Elective
|
|
Course Delivery Method
|
Face To Face
|
|
Objectives of the Course
|
Know about the natural products as drugs and their biosynthesis
Learn various natural product discovery strategies
Develop a strategy for the discovery/biosynthesis of natural products as a team.
|
|
Course Content
|
In this course, the natural products discovery and their biosynthesis will be introduced. It covers various natural products discovery strategies including genome mining, strain engineering, combinatorial biosynthesis, metagenomics, co-cultivation, cell-free systems and traditional approach. It also provides a brief introduction to drug development process. Students are expected to have a term project regarding the discovery and/or biosynthesis of novel natural products.
|
|
Course Methods and Techniques
|
|
|
Prerequisites and co-requisities
|
None
|
|
Course Coordinator
|
Asist Prof.Dr. ÖZKAN FİDAN ozkan.fidan@agu.edu.tr
|
|
Name of Lecturers
|
Asist Prof.Dr. ÖZKAN FİDAN
|
|
Assistants
|
None
|
|
Work Placement(s)
|
No
|
Recommended or Required Reading
Course Category
|
Engineering
|
%25
|
|
|
Science
|
%50
|
|
|
Health
|
%25
|
|
|
Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
|
In-Term Studies
|
|
Quiz/Küçük Sınav
|
1
|
%
25
|
|
Proje/Çizim
|
1
|
%
20
|
|
Sunum/Seminer
|
2
|
%
20
|
|
Final examination
|
1
|
%
35
|
|
Total
|
5
|
%
100
|
ECTS Allocated Based on Student Workload
|
Activities
|
Total Work Load
|
|
Yazılı Sınav
|
1
|
15
|
15
|
|
Grup Projesi
|
4
|
8
|
32
|
|
Sunum için Hazırlık
|
5
|
5
|
25
|
|
Sunum
|
1
|
5
|
5
|
|
Proje
|
1
|
6
|
6
|
|
Okuma
|
15
|
2
|
30
|
|
Araştırma
|
15
|
3
|
45
|
|
Yüz Yüze Ders
|
15
|
3
|
45
|
|
Final Sınavı
|
1
|
22
|
22
|
|
Total Work Load
| |
|
Number of ECTS Credits 7,5
225
|
Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
| No | Learning Outcomes |
|
1
| Interpret natural product biosynthesis. |
|
2
| Describe traditional and current natural product discovery techniques. |
|
3
| Explain drug development process briefly. |
|
4
| Apply the natural product discovery techniques to generate novel compounds as part of a team. |
Weekly Detailed Course Contents
| Week | Topics | Study Materials | Materials |
| 1 |
Introduction to natural products
|
|
|
| 2 |
Sources of natural products
|
|
|
| 3 |
Differences between natural products and synthetics
|
|
|
| 4 |
Natural product discovery: Traditional approach
|
|
|
| 5 |
Natural product discovery: Genome mining
|
|
|
| 6 |
Natural product discovery: Strain engineering
|
|
|
| 7 |
Natural product discovery: Co-cultivation
|
|
|
| 8 |
Midterm
|
|
|
| 9 |
Natural product discovery: Combinatorial biosynthesis
|
|
|
| 10 |
Natural product discovery: Cell-free systems
|
|
|
| 11 |
Natural product discovery: Metagenomics
|
|
|
| 12 |
Term project discussions
|
|
|
| 13 |
Drug development
|
|
|
| 14 |
Student Presentations
|
|
|
| 15 |
Student Presentations
|
|
|
| 16 |
Final exam
|
|
|
Contribution of Learning Outcomes to Programme Outcomes
Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant
https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=77955&lang=en