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Language of Instruction
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English
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Level of Course Unit
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Master's Degree
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Department / Program
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BIOENGINEERING
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Type of Program
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Formal Education
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Type of Course Unit
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Elective
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Course Delivery Method
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Face To Face
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Objectives of the Course
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This course aims at the comprehensive view of the stem cell therapy with both embryonic and adult stem cells including characteristics at cellular and molecular levels, signaling transduction, stem cell interactions with their microenvironment and their role in regenerative medicine. The purpose of this course is to give point to advanced approaches of stem cell therapy involving in stem cell transplantation as a standard treatment for vascular, cardiac and bone disorders. Also, this course emphasizes the potential uses and limitations of stem cells for the treatment of hematological diseases, and ethical issues of stem cell applications in the regenerative medicine.
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Course Content
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Course objectives are to:
-Defining the current knowledge potential use and development of stem cell therapy and regenerative medicine.
- Describing different types of stem cells and their specific characteristics, and also methods of applications to replace damaged or destroyed cells including tissue engineering.
- Explaining the advanced applications of stem cell therapy to human diseases.
- Evaluating current theories, methods and techniques within the research field and their advanced application in the stem cell therapy and tissue engineering.
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Course Methods and Techniques
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In this course, student-centered and teacher-centered methods of instructions will be used together. The basic principles of various stem cell techniques will be covered in the lectures. Each student will be asked to present an example of the stem cell techniques and regenerative medicine.
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Prerequisites and co-requisities
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None
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Course Coordinator
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None
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Name of Lecturers
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Asist Prof.Dr. Mesude Bicer mesude.bicer@agu.edu.tr
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Assistants
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None
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Work Placement(s)
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No
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Recommended or Required Reading
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Resources
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Weekly Schedule: 1 Introduction to stem cell technology and regenerative medicine 2 Embryonic stem cells (ESCs) and human ESCs in regenerative medicine 3 Induced pluripotent stem cells (iPSCs) and their clinical applications 4 Mesenchymal stem cells (MSCs) and their recent therapeutic applications 5 Stem Cell Bioengineering for iPSCs and MSCs 6 Natural, synthetic and composite biomaterials, tissue and organ production via decellularization in 2D and 3D 7 Fall Break 8 Active Learning Week Activity: Group work and Group Discussion 9 Midterm 10 Vascular tissue engineering with stem cell technology and regenerative medicine 11 Cardiac tissue engineering with stem cell technology and regenerative medicine 12 Bone tissue engineering with stem cell technology and regenerative medicine 13 Immunology, immunomodulation and anti-inflammation from stem cells to regenerative medicine introduction 14 Use of large animal models and non-human primate models for regenerative medicine research, Ethical
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Course Notes
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The Science of Stem Cells by Jonathan M. W. Slack, Print ISBN:9781119235156 Online ISBN:9781119235293 |DOI:10.1002/9781119235293 © 2018 John Wiley & Sons, Inc.
Stem Cells Biology and Application by Mark Clarke, Jonathan Frampton, ISBN 9780815345114, Published July 27, 2020 by Garland Science 462 Pages 456 Color Illustrations.
Regenerative Medicine and Stem Cell Biology by Nagwa El-Badri, Springer Nature Switzerland AG 2020, DOI:10.1007/978-3-030-55359-3.
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Documents
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The Science of Stem Cells by Jonathan M. W. Slack, Print ISBN:9781119235156 Online ISBN:9781119235293 |DOI:10.1002/9781119235293 © 2018 John Wiley & Sons, Inc. Stem Cells Biology and Application by Mark Clarke, Jonathan Frampton, ISBN 9780815345114, Published July 27, 2020 by Garland Science 462 Pages 456 Color Illustrations. Regenerative Medicine and Stem Cell Biology by Nagwa El-Badri, Springer Nature Switzerland AG 2020, DOI:10.1007/978-3-030-55359-3.
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Assignments
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Term project presentation and term project report
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Exams
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Midterm and final exam
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Course Category
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Engineering
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%40
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Science
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%30
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Health
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%30
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