Course Details

Course Information

Semester	Course Unit Code	Course Unit Title	T+P+L	Credit	Number of ECTS Credits	Last Updated Date
7	MBG436	MILESTONE DISCOVERIES IN PHYSIOLOGY AND MEDICINE	3+0+0	3	5	14.05.2025

Course Details

Language of Instruction	English
Level of Course Unit	Bachelor's Degree
Department / Program	MOLECULAR BIOLOGY AND GENETICS
Type of Program	Formal Education
Type of Course Unit	Elective
Course Delivery Method	Face To Face
Objectives of the Course	"Milestone Discoveries in Physiology and Medicine" explores the challenges and problem-solving approaches behind Nobel-recognized research in Physiology or Medicine. The course highlights innovative research processes and methodologies that drive scientific breakthroughs.
Course Content	This course examines the collaborative efforts behind recent Nobel Prize-winning discoveries, focusing on the scientific advancements that enabled groundbreaking research. It highlights the Nobel-recognized research process and its impact on future scientific investigations and medical practices.
Course Methods and Techniques	Lectures, particular talks by prominent scientists, quizzes, articles will be included within the course content. Additionally, each student (as an individual or within groups ) is responsible from presenting an article in front of the class.
Prerequisites and co-requisities	None
Course Coordinator	None
Name of Lecturers	Asist Prof.Dr. Nurettin AYVALI nurettin.ayvali@agu.edu.tr
Assistants	None
Work Placement(s)	No

Recommended or Required Reading

Resources
Course Notes	Lectures and some of the notes (on papers) would be shared.
Documents	Canvas.

Planned Learning Activities and Teaching Methods

Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria

In-Term Studies	Quantity	Percentage
Yarıyıl İçi Çalışmalarının Başarı Notunun Katkısı	1	% 20
Quiz/Küçük Sınav	8	% 30
Sunum/Seminer	1	% 20
Final examination	1	% 20
Diğer (Staj vb.)	1	% 10
Total	12	% 100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration	Total Work Load
Yazılı Sınav	1	2	2
Grup Sunumu	1	2	2
Ders Dışı Sınav	6	2	12
Sunum için Hazırlık	1	15	15
Kısa Sınav	6	3	18
Okuma	12	2	24
Kişisel Çalışma	12	3	36
Yüz Yüze Ders	1	2	2
Ders Dışı Ara Sınav	1	3	3
Derse Devam	14	2	28
Final Sınavı	1	3	3
Total Work Load			Number of ECTS Credits 5 145

Course Learning Outcomes: Upon the successful completion of this course, students will be able to:

No	Learning Outcomes
1	Critically evaluate prominent literature relevant to the Nobel Prizes.
2	Develop basic understanding of the scientific research, including hypothesis generation, experimental design and innovative problem-solving approaches.
3	Identify the adopted scientific methodology within the Nobel-winning research.
4	Appraise the scientific implications of these discoveries and their impact on future research and medical practices.
5	Assess the societal and ethical implications, and relate to their broader impact on cultural, legal, and/or moral frameworks.

Weekly Detailed Course Contents

Week	Topics	Materials
1	Introduction to the Nobel Prizes, Breakthroughs That Shaped Science and Technology (and Humans). Social Responsibility of a scientist/inventor …	Regarding documents, please check the "Yöntem ve Teknikleri " part of this course catalog.
2	Benefits of studying Nobel-recognized research with in-depth approach. Criteria regarding how we should approach towards analyzing Nobel-recognized milestone papers
3	The molecular mechanisms underlying how cells adapt to variations in oxygen supply and milestone papers
6	Discoveries of receptors for temperature and touch
7	The discovery that mature cells can be reprogrammed to become pluripotent (iPSCs)
8	Lecture-free week
9	Midterm
10	The discovery of microRNA and its role in post-transcriptional gene regulation
11	Discovery of RNA interference – a gene-silencing mechanism mediated by double-stranded RNA
12	First demonstration of how CRISPR-Cas9 could be repurposed as a precise gene-editing tool
13	Overlooked contributors and/or prominent scientists who didn’t get Nobel Prize. Future Directions: Potential nominations based on the recent research.
14	Ethical Considerations & "Article" Reading, Data analysis and interpretation, limitations of a particular research, presenting ...

Contribution of Learning Outcomes to Programme Outcomes

Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=77605&lang=en