Course Details

Course Information

Semester	Course Unit Code	Course Unit Title	T+P+L	Credit	Number of ECTS Credits	Last Updated Date
5	BENG437	BIOORGANIC & MEDICINAL CHEMISTRY	3+0+0	3	5	15.05.2025

Course Details

Language of Instruction	English
Level of Course Unit	Bachelor's Degree
Department / Program	MOLECULAR BIOLOGY AND GENETICS
Type of Program	Formal Education
Type of Course Unit	Elective
Course Delivery Method	Face To Face
Objectives of the Course	This course represents: How to measure the activity of enzymes and receptors; Methods for modeling a drug’s half-life; Techniques for discovering molecules with desired biological activity; Approaches for optimizing a molecule into a safe and effective drug
Course Content	This course covers the contemporary topics of bioorganic and medicinal chemistry such as QSAR, Drug-receptor interactions, enzymes and molecule interactions, computer aided drug design, pharmacokinetics and click chemistry. This course also covers the understanding relationship between drugs/therapeutics and biological systems.
Course Methods and Techniques	Face-to-face lecture, midterm exam, final exam, project submission&presentation
Prerequisites and co-requisities	None
Course Coordinator	Asist Prof.Dr. İSMAİL AKÇOK ismail.akcok@agu.edu.tr
Name of Lecturers	None
Assistants	None
Work Placement(s)	No

Recommended or Required Reading

Resources	Fundamentals of Medicinal Chemistry, Gareth Thomas, Wiley, 2003
Course Notes	Fundamentals of Medicinal Chemistry, Gareth Thomas

Planned Learning Activities and Teaching Methods

Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria

Veri yok

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration	Total Work Load
Yazılı Sınav	1	10	10
Grup Sunumu	1	14	14
Sınıf İçi Aktivitesi	14	1	14
Proje	1	14	14
Araştırma	14	1	14
Kişisel Çalışma	14	2	28
Öğretici Sunum/Açıklama	1	3	3
Yüz Yüze Ders	14	3	42
Final Sınavı	1	10	10
Total Work Load			Number of ECTS Credits 5 149

Course Learning Outcomes: Upon the successful completion of this course, students will be able to:

No	Learning Outcomes
1	to describe the fundamentals of medicinal chemistry
2	to classify the drug-receptor interactions
3	to recognize the biological targets
4	to recognize the drug metabolism
5	to determine the bio-orthogonal chemistry and applications

Weekly Detailed Course Contents

Week	Topics	Study Materials	Materials
1	* Introduction to the course * Explanation of expectations, assignments, grading * What is Bioorganic Chemistry? * Bio-orthogonal Chemistry	Pre-reading the relevant focuments and textbok	Textbook
2	Biological Molecules		Relevant Chapter of textbook
3	* An introduction to Drugs and their Action	Reading textbook	Textbook
4	* An Introduction to Drug Discovery	Reading relevant chapter of textbook	Textbook
5	* The SAR and QSAR Approaches to Drug Design	Reading relevant chapter of textbook	Textbook
6	* Computer Aided Drug Design	Reading relevant chapter of textbook	Textbook
7	* Combinatorial Chemistry	Reading relevant chapter of textbook	Textbook
8	SPRING BREAK
9	*Selected Examples of Drug Action at some Common Target Areas	Reading relevant chapter of textbook	Textbook
10	Pharmacokinetics	Reading the relevant chapter of textbook	Textbook
11	Drug Metabolism	Reading relevant chapter of textbook	Textbook
12	An Introduction to Lead and Analogue Syntheses	Reading the relevant chapter of textbook	Textbook
13	Drug Development and Production	Reading the relevant chapter of textbook	Textbook
14	Specific case studies discussions	Reading the relevant chapter of textbook and research articles	Textbook and Research articles
15	Research Proposal Project Presentations & Final Report Submissions of the Projects

Contribution of Learning Outcomes to Programme Outcomes

Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=76579&lang=en