| Semester | Course Unit Code | Course Unit Title | T+P+L | Credit | Number of ECTS Credits | Last Updated Date |
| 6 | MBG306 | GENE REGULATION | 4+0+0 | 4 | 7 | 19.05.2026 |
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Language of Instruction
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English
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Level of Course Unit
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Bachelor's Degree
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Department / Program
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MOLECULAR BIOLOGY AND GENETICS
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Type of Program
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Formal Education
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Type of Course Unit
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Compulsory
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Course Delivery Method
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Face To Face
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Objectives of the Course
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Providing an understanding of the regulation of transcription in eukaryotic organisms
Providing the basics of post-transcriptional regulation
Providing the structure, formation and function of microRNAs
Making students understand how the process of translation is controlled.
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Course Content
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This course will emphasize the basics and mechanisms of eucaryotic gene regulation with a specific focus on newly emerging topics. This course will be using current literatüre together with a main textbook. Topics will include transcriptional regulation of eukaryotic gene expression including cis elements (promoters, enhancers and insulators) and trans elements (transcription factors), key modules of differential gene expression, chromatin remodeling, the posttranscriptional regulation of gene expression including RNA interference, tranlastional regulation etc.
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Course Methods and Techniques
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Individual presentations
Midterm
Final exam
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Prerequisites and co-requisities
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( MBG208 )
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Course Coordinator
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None
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Name of Lecturers
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Associate Prof.Dr. AYSUN ADAN aysun.adan@agu.edu.tr
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Assistants
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None
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Work Placement(s)
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No
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Recommended or Required Reading
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Resources
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Mechanisms of Gene Regulation by Carsten Carlberg and Ferdidand Molnar (2016)
Genes XII
Molecular Biology of the Gene
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Course Notes
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Course materials will be shared via Canvas
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Documents
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canvas
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Assignments
|
canvas
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Exams
|
yüz yüze sınıf ortamında
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Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
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In-Term Studies
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Quiz/Küçük Sınav
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1
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%
35
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Sunum/Seminer
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1
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%
25
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Final examination
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1
|
%
40
|
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Total
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3
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%
100
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ECTS Allocated Based on Student Workload
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Activities
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Total Work Load
|
|
Tartışma
|
1
|
3
|
3
|
|
Yazılı Sınav
|
1
|
20
|
20
|
|
Sınıf İçi Aktivitesi
|
1
|
3
|
3
|
|
Sunum için Hazırlık
|
1
|
5
|
5
|
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Okuma
|
1
|
2
|
2
|
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Araştırma
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1
|
2
|
2
|
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Kişisel Çalışma
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14
|
10
|
140
|
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Final Sınavı
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1
|
40
|
40
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Total Work Load
| |
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Number of ECTS Credits 7
215
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Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
| No | Learning Outcomes |
|
1
| Have a knowledge of detailed structure of genes, chromatin organization, transcription factors and how they are regulated. |
|
2
| Identify the key components, mechanisms and multi levels of gene expression and its complexity |
|
3
| The effects of transcription factors, their co-regulators and non coding RNAs on the regulation of eukaryotic genes. |
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4
| Have knowledge of designing, performing and analyzing gene expression related experiments. |
Weekly Detailed Course Contents
| Week | Topics | Study Materials | Materials |
| 1 |
Discussion about syllabus and the structure of the course
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| 2 |
Overview: what is gene expression?
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| 3 |
Transcriptional Regulation I
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| 4 |
Transcriptional Regulation II
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| 5 |
Transcriptional Regulation III
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| 6 |
Chromatin View I
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| 7 |
Chromatin View II
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| 8 |
Chromatin View III
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| 9 |
All topics will be summarized and evaluated
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| 10 |
Related research topic will be discussed
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| 11 |
Translational control
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| 12 |
Non-coding RNA
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| 13 |
Individual Research Presentations
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| 14 |
Individual Research Presentations
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Sustainable Development Goals
Contribution of Learning Outcomes to Programme Outcomes
Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant
https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=76140&lang=en