Course Details

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Course Information
SemesterCourse Unit CodeCourse Unit TitleT+P+LCreditNumber of ECTS CreditsLast Updated Date
6MBG306GENE REGULATION 4+0+04714.05.2025

 
Course Details
Language of Instruction English
Level of Course Unit Bachelor's Degree
Department / Program MOLECULAR BIOLOGY AND GENETICS
Type of Program Formal Education
Type of Course Unit Compulsory
Course Delivery Method Face To Face
Objectives of the Course O1. Providing an understanding of the regulation of transcription in eukaryotic organisms
O2. Providing the basics of post-transcriptional regulation
O3. Providing the structure, formation and function of microRNAs
O4. Making students understand how the process of translation is controlled.
Course Content This course will emphasize the basics and mechanisms of eucaryotic gene regulation with a specific focus on newly emerging topics. This course will be using current literatüre together with a main textbook. Topics will include transcriptional regulation of eukaryotic gene expression including cis elements (promoters, enhancers and insulators) and trans elements (transcription factors), key modules of differential gene expression, chromatin remodeling, the posttranscriptional regulation of gene expression including RNA interference, tranlastional regulation etc.
Course Methods and Techniques Assignments as small-quizzes
Individual presentations
Midterm
Final exam
Prerequisites and co-requisities ( MBG208 )
Course Coordinator None
Name of Lecturers Associate Prof.Dr. AYSUN ADAN aysun.adan@agu.edu.tr
Assistants None
Work Placement(s) No

Recommended or Required Reading
Resources Mechanisms of Gene Regulation by Carsten Carlberg and Ferdidand Molnar (2016)
Genes XII
Molecular Biology of the Gene
Course Notes Course materials will be shared via Canvas
Documents canvas
Assignments canvas
Exams yüz yüze sınıf ortamında

Course Category
Science %70
Health %30

Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria
In-Term Studies Quantity Percentage
Quiz/Küçük Sınav 1 % 35
Sunum/Seminer 1 % 25
Final examination 1 % 40
Total
3
% 100

 
ECTS Allocated Based on Student Workload
Activities Quantity Duration Total Work Load
Tartışma 1 3 3
Yazılı Sınav 1 20 20
Sınıf İçi Aktivitesi 1 3 3
Sunum için Hazırlık 1 5 5
Okuma 1 2 2
Araştırma 1 2 2
Kişisel Çalışma 14 10 140
Final Sınavı 1 40 40
Total Work Load   Number of ECTS Credits 7 215

 
Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
NoLearning Outcomes
1 Have a knowledge of detailed structure of genes, chromatin organization, transcription factors and how they are regulated.
2 Identify the key components, mechanisms and multi levels of gene expression and its complexity
3 The effects of transcription factors, their co-regulators and non coding RNAs on the regulation of eukaryotic genes.
4 Have knowledge of designing, performing and analyzing gene expression related experiments.

 
Weekly Detailed Course Contents
WeekTopicsStudy MaterialsMaterials
1 Discussion about syllabus and the structure of the course
2 Overview: what is gene expression?
3 Transcriptional Regulation I
4 Transcriptional Regulation II
5 Transcriptional Regulation III
6 Chromatin View I
7 Chromatin View II
8 Chromatin View III
9 All topics will be summarized and evaluated
10 Related research topic will be discussed
11 Translational control
12 Non-coding RNA
13 Individual Research Presentations
14 Individual Research Presentations

 
Contribution of Learning Outcomes to Programme Outcomes
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10
All 3 5 5 4 4 2 4 5 3 4
C1 3 5 3 3 4 2 3 3 3 3
C2 3 5 5 4 4 2 4 5 3 4
C3 3 5 5 4 4 2 4 5 3 4
C4 3 5 5 4 4 2 4 5 3 4

  Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

  
  https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=76140&lang=en
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