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Language of Instruction
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English
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Level of Course Unit
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Bachelor's Degree
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Department / Program
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MOLECULAR BIOLOGY AND GENETICS
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Type of Program
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Formal Education
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Type of Course Unit
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Elective
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Course Delivery Method
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Face To Face
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Objectives of the Course
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1. Gain insights in the basic concepts of cellular signal transduction
2. Describe the signal transduction mechanisms of different types of receptors
3. Learn how signal integration is accomplished in target cells
4. Learn the importance of cell signaling in gene regulation
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Course Content
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The course will focus primarily on the activation of cell surface receptors, interaction of signaling molecules with the activated receptors and the generation of secondary messengers and intracellular ionic currents. Student will learn the various cell signaling pathways and networks in health and disease.
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Course Methods and Techniques
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Basic concepts and theoretical information are directly transferred by the instructor.
It is used especially in the introductory topics of the course (atomic structure, macromolecules, cell components, etc.).
Advantage: A lot of information is transferred in a short time.
Questions and answers are used to increase the active participation of students in the course.
It is applied at the end of the subject or during the course to gather the attention of the students and reinforce the information.
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Prerequisites and co-requisities
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None
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Course Coordinator
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None
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Name of Lecturers
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Instructor Dr. Demet Şaylan
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Assistants
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None
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Work Placement(s)
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No
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Recommended or Required Reading
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Resources
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Biochemistry of Signal Transduction and Regulation. 2014. Wiley-VCH. Gerhard Krauss.
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Course Notes
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This course focuses on cellular communication processes that begin with the activation of cell surface receptors and extend to the regulation of intracellular signaling pathways. Students will learn how the activation of signaling molecules resulting from ligand-receptor interactions, the production of secondary messengers, and ionic currents affect cellular functions. In addition, how these signaling pathways play a role in physiological processes and disease pathogenesis will be examined through sample pathways. The course aims to understand the effects of signaling networks on cell fate, proliferation, differentiation, and death at the molecular level.
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Documents
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Signal Transduction. 2014. Cold Spring Harbor Laboratory Press. Lewis Cantley, Tony Thunter, Richard Sever and Jeremy Thorner.
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Assignments
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canvas
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Course Category
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Mathematics and Basic Sciences
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Engineering
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Engineering Design
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Social Sciences
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Education
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Science
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Health
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Field
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