Course Details

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Course Information
SemesterCourse Unit CodeCourse Unit TitleT+P+LCreditNumber of ECTS CreditsLast Updated Date
7MBG409CANCER BIOLOGY3+0+03529.04.2026

 
Course Details
Language of Instruction English
Level of Course Unit Bachelor's Degree
Department / Program MOLECULAR BIOLOGY AND GENETICS
Type of Program Formal Education
Type of Course Unit Elective
Course Delivery Method Face To Face
Objectives of the Course O1. Providing the details of basic principles of cancer development at the level of
molecular and cell biology
O2. Making the students familiar with the basic concepts applied to cancer
diagnosis and treatment
O3.Providing basic knowledge in the field in order to follow current literature
O4. Giving students main knowledge behind the difficulties in the treatment of
cancer
Course Content This course will emphasize the steps of carcinogenesis at the molecular level by specifically focusing on the hallmarks of cancer cells. Oncogenes, tumor suppressor genes, cell cycle regulation, angiogenesis, metastasis and invasion, tumor environment, multi drug resistance mechanisms, cancer stem cell and targeting of all steps of carcinogenesis for therapeutic purposes will be covered throught the lecture.
Course Methods and Techniques Students-based active learning
Assignments as small-quizzes
Individual presentations
Midterm
Final exam
Prerequisites and co-requisities None
Course Coordinator None
Name of Lecturers Associate Prof. AYSUN ADAN
Assistants None
Work Placement(s) No

Recommended or Required Reading
Resources Principles of Cancer Biology: Pearson New International Edition, Lewis J. Kleinsmith, 2014
Cancer signaling : from molecular biology to targeted therapy / Christoph Wagener, Carol Stocking, and Oliver Müller
The Molecular Biology of Cancer: A bridge from bench to Bedside/ Stella Pelengaris and Michael Khan
Recent scientific papers
Course Notes Principles of Cancer Biology: Pearson New International Edition, Lewis J. Kleinsmith,2014?
Cancer signaling : from molecular biology to targeted therapy / Christoph Wagener, Carol Stocking, and Oliver Müller (Available in the library)?
The Molecular Biology of Cancer: A bridge from bench to Bedside/ Stella Pelengaris and Michael Khan (Available in the library)?
Current Scientific articles related to topics

Course Category
Science %70
Health %30

Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria
In-Term Studies Quantity Percentage
Yarıyıl İçi Çalışmalarının Başarı Notunun Katkısı 1 % 30
Sunum/Seminer 1 % 25
Final examination 1 % 45
Total
3
% 100

 
ECTS Allocated Based on Student Workload
Activities Quantity Duration Total Work Load
Tartışma 1 6 6
Okuma 1 13 13
Araştırma 2 15 30
Ders dışı çalışma 2 13 26
Yüz Yüze Ders 3 13 39
Ders Dışı Ara Sınav 1 10 10
Final Sınavı 1 20 20
Total Work Load   Number of ECTS Credits 5 144

 
Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
NoLearning Outcomes
1 Define the differences between normal and cancer cells
2 Define the factors causing cancer
3 Define the mechanisms involved in cancer development
4 Have knowledge of molecular approaches used in cancer treatment
5 Have knowledge of scientific databases and sources, project writing and presentation skills for students

 
Weekly Detailed Course Contents
WeekTopicsStudy MaterialsMaterials
1 Discussion about the syllabus and topics covered in this course
2 Hallmarks of Cancer
3 Carcinogenesis
4 Tumor Suppressor Genes and Oncogenes
5 Cell Cycle and Cancer
6 Cell Death Mechanisms I
7 Cell Death Mechanisms II
8 LFW-In class activities
9 Midterm
10 Invasion and Metastasis
11 Angiogenesis
12 Tumor Microenviroment
13 Cancer Stem cells
14 Multi Drug Resistance Mechanisms

 
Contribution of Learning Outcomes to Programme Outcomes
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10
All 4 5 4 4 4 3 4 5 3 3
C1 3 5 3 3 4 2 3 5 3 3
C2 3 5 5 4 4 2 4 5 3 4
C3 3 5 5 4 4 2 4 5 3 4
C4 3 5 5 4 4 2 4 5 3 4
C5 5 5 5 5 5 5 5 5 4 5

  Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

  
  https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=75941&lang=en
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