Course Details

Course Information

Semester	Course Unit Code	Course Unit Title	T+P+L	Credit	Number of ECTS Credits	Last Updated Date
5	BENG427	TISSUE BIOMATERIAL INTERACTION	3+0+0	3	5	14.05.2025

Course Details

Language of Instruction	English
Level of Course Unit	Bachelor's Degree
Department / Program	BIOENGINEERING
Type of Program	Formal Education
Type of Course Unit	Elective
Course Delivery Method	Face To Face
Objectives of the Course	This course is about the comprehensive view of the three pertinent interfaces between the body and the biomaterial between the body and living cells, and between the cells and the biomaterial that are critical in the development of tissue- engineered products that incorporate living cells within a biomaterial matrix. It covers basic technology involving in implantable biomedical devices. Also, this course emphasizes the importance of the body’s wound-healing response and the structure of biomaterials.
Course Content	Course objectives are to: -Defining the protein-surface interactions - Describing the blood-biomaterial interactions - Explaining the immune system, inflammation, and infection - Evaluating biomaterial responses to implantation
Course Methods and Techniques	In this course, student-centered and teacher-centered methods of instructions will be used together. The basic principles of biomaterial surface engineering will be covered in the lectures. Each student will be asked to present an example of the tissue-biomaterial interactions.
Prerequisites and co-requisities	None
Course Coordinator	None
Name of Lecturers	Asist Prof.Dr. Mesude Bicer mesude.bicer@agu.edu.tr
Assistants	None
Work Placement(s)	No

Recommended or Required Reading

Resources	Course content includes: -Describe protein-surface interactions -Explain blood-biomaterial interactions -Explain the immune system, inflammation, and infection -Evaluate biomaterial responses to implantation
Course Notes	In this course, student-centered and teacher-centered methods of instructions will be used together. The basic principles of biomaterial surface engineering will be covered in the lectures. Each student will be asked to present an example of the tissue-biomaterial interactions.
Documents	An introduction to Tissue-Biomaterial Interactions by Kay C. Dee, David A. Puleo, Rena Bizios. ISBN:978-0-471-25394-5
Assignments	Term project presenttion and term project report
Exams	Midterm an final exams

Course Category

Planned Learning Activities and Teaching Methods

Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria

In-Term Studies	Quantity	Percentage
Yarıl yılSonu Sınavı/Dönem Projesinin Başarı Notuna Katkısı	1	% 10
Quiz/Küçük Sınav	1	% 30
Ödev	1	% 10
Sunum/Seminer	1	% 10
Final examination	1	% 40
Total	5	% 100

ECTS Allocated Based on Student Workload

Activities	Quantity	Duration	Total Work Load
Araştırma Ödevi	1	3	3
Tartışma	14	3	42
Yazılı Sınav	3	3	9
Grup Sunumu	1	3	3
Sınıf İçi Aktivitesi	14	1	14
Sunum	1	3	3
Rapor	1	3	3
Yüz Yüze Ders	14	3	42
Total Work Load			Number of ECTS Credits 5 119

Course Learning Outcomes: Upon the successful completion of this course, students will be able to:

No	Learning Outcomes
1	Explain fundamental biological processes that influence cutting-edge procedures.
2	Define various types of molecular-level events that happen at the tissue- implant interface.
3	Interpret about the selected material for biological and physiological consequences.
4	Advance biomaterial surface engineering as examples of tissue-biomaterial interactions.

Weekly Detailed Course Contents

Week	Topics	Study Materials	Materials
1	Introduction for Tissue Biomaterial Interaction
2	Biomaterials and Proteins
3	Protein-Surface Interactions
4	Blood-Biomaterial Interactions and Coagulation
5	Inflammation and Infection
6	The Immune System and Inflammation
7	Wound Healing
8	Spring Break
9	Active Learning Week
10	Biomaterial Responses to Implantation
11	Biomaterial Surface Engineering and the Physiological Environment
12	Biocompatibility
13	Example of tissue-biomaterial interactions: Opening Occluded Vessels: Vascular Grafts, Intimal Hyperplasia
14	Example of tissue-biomaterial interactions: Replacing Joints and Teeth
15	Student presentations -Term Project Presentation

Recommended Optional Programme Components

Veri yok

Contribution of Learning Outcomes to Programme Outcomes

Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant

https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=72236&lang=en