| Semester | Course Unit Code | Course Unit Title | T+P+L | Credit | Number of ECTS Credits |
| 4 | BENG552 | NATURAL PRODUCT DISCOVERY AND BIOSYNTHESIS | 3+0+0 | 3 | 7,5 |
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Language of Instruction
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English
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Level of Course Unit
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Master's Degree
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Department / Program
|
BIOENGINEERING
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Type of Program
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Formal Education
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Type of Course Unit
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Elective
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Course Delivery Method
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Face To Face
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Objectives of the Course
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Know about the natural products as drugs and their biosynthesis
Learn various natural product discovery strategies
Develop a strategy for the discovery/biosynthesis of natural products as a team.
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Course Content
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In this course, the natural products discovery and their biosynthesis will be introduced. It covers various natural products discovery strategies including genome mining, strain engineering, combinatorial biosynthesis, metagenomics, co-cultivation, cell-free systems and traditional approach. It also provides a brief introduction to drug development process. Students are expected to have a term project regarding the discovery and/or biosynthesis of novel natural products.
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Course Methods and Techniques
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Prerequisites and co-requisities
|
None
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Course Coordinator
|
Asist Prof.Dr. ÖZKAN FİDAN ozkan.fidan@agu.edu.tr
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Name of Lecturers
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None
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Assistants
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None
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Work Placement(s)
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No
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Recommended or Required Reading
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Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
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In-Term Studies
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Quiz/Küçük Sınav
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1
|
%
25
|
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Proje/Çizim
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1
|
%
20
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Sunum/Seminer
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2
|
%
20
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Final examination
|
1
|
%
35
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Total
|
5
|
%
100
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ECTS Allocated Based on Student Workload
|
Activities
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Total Work Load
|
|
Yazılı Sınav
|
1
|
15
|
15
|
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Grup Projesi
|
4
|
8
|
32
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Sunum için Hazırlık
|
5
|
5
|
25
|
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Sunum
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1
|
5
|
5
|
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Proje
|
1
|
6
|
6
|
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Okuma
|
15
|
2
|
30
|
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Araştırma
|
15
|
3
|
45
|
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Yüz Yüze Ders
|
15
|
3
|
45
|
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Final Sınavı
|
1
|
18
|
18
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Total Work Load
| |
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Number of ECTS Credits 7,5
221
|
Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
| No | Learning Outcomes |
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1
| Interpret natural product biosynthesis. |
|
2
| Describe traditional and current natural product discovery techniques. |
|
3
| Explain drug development process briefly. |
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4
| Apply the natural product discovery techniques to generate novel compounds as part of a team. |
Weekly Detailed Course Contents
| Week | Topics | Study Materials | Materials |
| 1 |
Introduction to natural products
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| 2 |
Sources of natural products
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| 3 |
Differences between natural products and synthetics
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| 4 |
Natural product discovery: Traditional approach
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| 5 |
Natural product discovery: Genome mining
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| 6 |
Natural product discovery: Strain engineering
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| 7 |
Natural product discovery: Co-cultivation
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| 8 |
Midterm
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| 9 |
Natural product discovery: Combinatorial biosynthesis
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| 10 |
Natural product discovery: Cell-free systems
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| 11 |
Natural product discovery: Metagenomics
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| 12 |
Term project discussions
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| 13 |
Drug development
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| 14 |
Student Presentations
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| 15 |
Student Presentations
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| 16 |
Final exam
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Contribution of Learning Outcomes to Programme Outcomes
Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant
https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=77955&lang=en