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Language of Instruction
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English
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Level of Course Unit
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Master's Degree
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Department / Program
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BIOENGINEERING
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Type of Program
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Formal Education
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Type of Course Unit
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Elective
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Course Delivery Method
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Face To Face
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Objectives of the Course
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Discussing Genome Editing History: ZNF and TALEN, CRISPR
Defining Prokaryotic Adaptive Immune System and CRISPR-Cas9 Technology Describing CRISPR-based Functional Analysis of Genes; CRISPR/Cas9 for Human Therapeutic (Cancer Therapy, mono-genetic diseases).
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Course Content
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The objective of this course is to introduce the concept of genome editing technology. In this course, introduced to the history of genome editing technologies (ZNF, TALEN, and CRISPR/Cas9), as well as numerous genome editing methodologies, design of CRISPR experiments (sgRNA, vector selection or adoption of the vector-free system, screening strategy, CRISPR efficiency, specificity, and safety, etc) from the beginning, CRISPR-mediated genome editing has opened doors to cure incurable human diseases and the extent to which CRISPR-mediated genome editing provides hope for these diseases will be covered. Also, the uses of CRISPR/Cas9-mediated genome editing in a wide spectrum of studies will be covered. Finally, there will be a discussion of the ethical aspects of genome editing technology
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Course Methods and Techniques
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Prerequisites and co-requisities
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None
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Course Coordinator
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None
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Name of Lecturers
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None
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Assistants
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None
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Work Placement(s)
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No
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Recommended or Required Reading
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