Course Details

MILESTONE DISCOVERIES IN PHYSIOLOGY AND MEDICINE

MBG436

Course Information
SemesterCourse Unit CodeCourse Unit TitleT+P+LCreditNumber of ECTS Credits
7MBG436FİYOLOKİ VE TIPTA DÖNÜM NOKTASI KEŞİFLER3+0+035

Course Details
Language of Instruction English
Level of Course Unit Bachelor's Degree
Department / Program MOLECULAR BIOLOGY AND GENETICS
Type of Program Formal Education
Type of Course Unit Elective
Course Delivery Method Face To Face
Objectives of the Course "Milestone Discoveries in Physiology and Medicine" explores the challenges and problem-solving approaches behind Nobel-recognized research in Physiology or Medicine. The course highlights innovative research processes and methodologies that drive scientific breakthroughs.
Course Content This course examines the collaborative efforts behind recent Nobel Prize-winning discoveries, focusing on the scientific advancements that enabled groundbreaking research. It highlights the Nobel-recognized research process and its impact on future scientific investigations and medical practices.
Key topics include:
Discovery of RNA interference – a gene-silencing mechanism mediated by double-stranded RNA
First demonstration of how CRISPR-Cas9 could be repurposed as a precise gene-editing tool
The discovery that mature cells can be reprogrammed to become pluripotent (iPSCs)
The discovery of cells’ oxygen sensing machinery
Discoveries of receptors for temperature and touch
The discovery of microRNA and its role in post-transcriptional gene regulation
Ethical Considerations & "Article" Reading, Data analysis and interpretation, limitations of a particular research, presenting ...
Course Methods and Techniques Lectures, particular talks by prominent scientists, quizzes, articles will be included within the course content. Additionally, each student (as an individual or within groups ) is responsible from presenting an article in front of the class.
Prerequisites and co-requisities None
Course Coordinator None
Name of Lecturers Asist Prof.Dr. Nurettin AYVALI nurettin.ayvali@agu.edu.tr
Assistants None
Work Placement(s) No

Recommended or Required Reading
Resources
Lectures and some of the notes (on papers) would be shared. Some of the course highlights and/or subjects regarding course content was indicated within the 'content' section.
Canvas.


Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria
In-Term Studies Quantity Percentage
Yarıyıl İçi Çalışmalarının Başarı Notunun Katkısı 1 % 20
Quiz/Küçük Sınav 8 % 30
Sunum/Seminer 1 % 20
Final examination 1 % 20
Diğer (Staj vb.) 1 % 10
Total
12
% 100

 
ECTS Allocated Based on Student Workload
Activities Quantity Duration Total Work Load
Yazılı Sınav 1 2 2
Grup Sunumu 1 2 2
Ders Dışı Sınav 6 2 12
Sunum için Hazırlık 1 15 15
Kısa Sınav 6 3 18
Okuma 12 2 24
Kişisel Çalışma 12 3 36
Yüz Yüze Ders 1 2 2
Ders Dışı Ara Sınav 1 3 3
Derse Devam 14 2 28
Final Sınavı 1 3 3
Total Work Load   Number of ECTS Credits 5 145

Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
NoLearning Outcomes
1 Critically evaluate prominent literature relevant to the Nobel Prizes.
2 Develop basic understanding of the scientific research, including hypothesis generation, experimental design and innovative problem-solving approaches.
3 Identify the adopted scientific methodology within the Nobel-winning research.
4 Appraise the scientific implications of these discoveries and their impact on future research and medical practices.
5 Assess the societal and ethical implications, and relate to their broader impact on cultural, legal, and/or moral frameworks.


Weekly Detailed Course Contents
WeekTopicsStudy MaterialsMaterials
1 In terms of content, the course flow and schedule are subject to change. For a detailed overview of the course topics, please refer to the "content" section of the course catalog. Regarding documents, please check the "Yöntem ve Teknikleri " part of this course catalog.


Contribution of Learning Outcomes to Programme Outcomes
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10
C1 5 5 3 4 5 2 4 4 4
C2 5 5 2 4 5 2 4 4 4
C3 5 5 2 4 5 2 5 5 4
C4 5 3 4 5 4 5 5 4
C5 3 3 3 3 5 5 4

Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant


https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=77605&lang=en