| Semester | Course Unit Code | Course Unit Title | T+P+L | Credit | Number of ECTS Credits |
| 5 | MBG419 | FUNCTIONAL GENOMICS | 3+0+0 | 3 | 5 |
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Language of Instruction
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English
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Level of Course Unit
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Bachelor's Degree
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Department / Program
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BIOENGINEERING
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Type of Program
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Formal Education
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Type of Course Unit
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Elective
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Course Delivery Method
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Face To Face
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Objectives of the Course
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1. To teach basic knowledge on genomics and studies on gene functions.
2. To explain theoretical and practical knowledge on experimental and computational techniques used in functional genomics.
3. To make student appreciate the importance of model organisms and their application.
4. To explain basic knowledge on functional genomics and systems biology in mammals and model organisms.
min 2 – max 4
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Course Content
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This course aims to give the fundamental principles within functional genomics, emphasizing the transcriptome and proteome to the students. The course also covers the contribution of functional genomics to systems biology and systems medicine, socio-ethical aspects of functional genomics in biomedicine and biotechnology, including perspectives on genetic risk information.
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Course Methods and Techniques
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Prerequisites and co-requisities
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None
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Course Coordinator
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Instructor Dr. Ömer Faruk Bay omerfaruk.bay@agu.edu.tr
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Name of Lecturers
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None
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Assistants
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None
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Work Placement(s)
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No
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Recommended or Required Reading
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Resources
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Bioinformatics and Functional Genomics (Jonathan Pevsner) Introduction to Genomics (Arthur M. Lesk) Bioinformatics, A Practical Handbook of Next Generation Sequencing and Its Applications (Lloyd Low, Martti Tammi)
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Course Category
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Mathematics and Basic Sciences
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%10
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Engineering
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%10
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Engineering Design
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%0
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Social Sciences
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%0
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Education
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%0
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Science
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%60
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Health
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%30
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Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"
Assessment Methods and Criteria
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In-Term Studies
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Yarıyıl İçi Çalışmalarının Başarı Notunun Katkısı
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1
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%
10
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Quiz/Küçük Sınav
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1
|
%
30
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Ödev
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1
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%
0
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Sunum/Seminer
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1
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%
20
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Final examination
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1
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%
40
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Total
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5
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%
100
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ECTS Allocated Based on Student Workload
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Activities
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Total Work Load
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Yazılı Sınav
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2
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2
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4
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F2F Dersi
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13
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3
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39
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Ev Ödevi
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1
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1
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1
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Sınıf İçi Aktivitesi
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5
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2
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10
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Ders Dışı Sınav
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2
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2
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4
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Sunum için Hazırlık
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1
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3
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3
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Sunum
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1
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1
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1
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Okuma
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1
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2
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2
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Tekrar Anlatım
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1
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3
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3
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Yazılım Deneyimi
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1
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2
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2
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Teslim
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1
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1
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1
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Yüz Yüze Ders
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13
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3
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39
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Ders Dışı Ara Sınav
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1
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1
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1
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Derse Devam
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1
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29
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29
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Final Sınavı
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1
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2
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2
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Total Work Load
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Number of ECTS Credits 5
141
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Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
| No | Learning Outcomes |
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1
| Explain the structure and function of human genome |
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2
| Define the basics of transcriptomics, proteomics and metabolomics concepts |
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3
| Describe biological networks and systems |
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4
| Explain the importance of model organisms in functional genomics and their specificities |
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5
| Value the issues and importance of legal and ethical aspects of the post-genome era |
Weekly Detailed Course Contents
| Week | Topics | Study Materials | Materials |
| 1 |
Introduction to MBG419
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| 2 |
From Genes to Genomes
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| 3 |
The Human Genome Project
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| 4 |
Principles of Genome Sequencing
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| 5 |
Sequencing Techniques and Logic
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| 6 |
Functional Genomics, The Central Dogma and Transcription Principles
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| 7 |
Transcriptomics Techniques and Logic
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| 8 |
Spring Break
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| 9 |
Active Learning Week
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| 10 |
Bulk RNAseq, Single-Cell RNAseq and Spatial Transcriptomics
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| 11 |
Applications of Functional Genomics,
Student Presentations
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| 12 |
Pathway Analysis
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| 13 |
Introduction to Proteomics
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| 14 |
Proteomics Techniques and Logic
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| 15 |
Recap
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Contribution of Learning Outcomes to Programme Outcomes
Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant
https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=72012&lang=en