Course Details

HUMAN GENETIC DISORDERS

MBG403

Course Information
SemesterCourse Unit CodeCourse Unit TitleT+P+LCreditNumber of ECTS Credits
5MBG403HUMAN GENETIC DISORDERS3+0+035

Course Details
Language of Instruction English
Level of Course Unit Bachelor's Degree
Department / Program BIOENGINEERING
Type of Program Formal Education
Type of Course Unit Elective
Course Delivery Method Face To Face
Objectives of the Course The aim of this course is to provide basic knowledge and skills to understand the molecular and cellular basis of inherited genetic disorders. It is aimed for students to develop a comprehensive understanding of the causes, clinical manifestations, diagnostic methods and current or developing treatment strategies of genetic diseases. In addition, it is aimed for students to evaluate ethical, social and psychological dimensions by analyzing the effects of genetic disorders on individuals and society.
Course Content This course provides an in-depth exploration of human genetic disorders, covering their causes, symptoms, diagnosis, and treatment options. Students will gain a comprehensive understanding of the underlying genetic mechanisms that contribute to various disorders and the impact they have on individuals and society.
Course Methods and Techniques Basic concepts and theoretical information are directly transferred by the instructor.

Especially introductory procedures in the sections (atomic structure, macromolecules, cell components, etc.) are used.

Advantage: Much information is transferred in a short time.
Question and answer is used to increase active reduction in the lesson.

It is applied at the end of the subject or during the lesson to collect the information and to reinforce the information.
Prerequisites and co-requisities None
Course Coordinator None
Name of Lecturers Instructor Dr. Demet Şaylan
Assistants None
Work Placement(s) No

Recommended or Required Reading
Resources Thompson & Thompson Genetics in Medicine
This course comprehensively examines the molecular basis, classification, diagnostic methods and treatment approaches of human genetic disorders. Students learn about genetic structures extending from DNA to genes and chromosomes, mutations and epigenetic mechanisms that play a role in the formation of hereditary diseases. They also recognize various types of genetic diseases such as monogenic and chromosomal disorders; and analyze the biological, psychological and ethical effects of these disorders on individuals and society. Modern approaches such as genetic counseling, prenatal diagnostic techniques, personalized medicine and gene therapy are also important components of the course. In this way, students gain the ability to evaluate genetic diseases from a holistic perspective.
https://canvas.agu.edu.tr/courses/4988/files
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Course Category
Mathematics and Basic Sciences %0
Engineering Design %0
Social Sciences %0
Education %0
Science %100
Health %0
Field %0

Planned Learning Activities and Teaching Methods
Activities are given in detail in the section of "Assessment Methods and Criteria" and "Workload Calculation"

Assessment Methods and Criteria
Veri yok

 
ECTS Allocated Based on Student Workload
Activities Quantity Duration Total Work Load
Tartışma 13 1 13
Yazılı Sınav 1 2 2
F2F Dersi 13 3 39
Grup Sunumu 1 2 2
Sınıf İçi Aktivitesi 13 1 13
Sunum 1 3 3
Tekrar Anlatım 1 3 3
Yüz Yüze Ders 13 3 39
Derse Devam 13 3 39
Final Sınavı 1 2 2
Total Work Load   Number of ECTS Credits 5 155

Course Learning Outcomes: Upon the successful completion of this course, students will be able to:
NoLearning Outcomes
1 Demonstrate a comprehensive understanding of the fundamental principles of genetics, including inheritance patterns and chromosomal abnormalities.
2 Identify and describe common human genetic disorders, including their genetic basis, symptoms, and prevalence in different populations.
3 Analyze the interplay between genetic and environmental factors in the development and manifestation of genetic disorders.


Weekly Detailed Course Contents
WeekTopicsStudy MaterialsMaterials
1 Introduction to Human Genetic Disorders İnsan Genetik Bozukluklarına Giriş dersi, kalıtımsal hastalıklarla ilgili ve genel anlayışlarına yönelik temel bilgiler sunar. Derse hazırlık olarak; DNA, gen, kromozomlar ve tüm türler gibi temel genetik kavramlara hakim olmak, Mendel kalıtımı ve kalıtım desenlerini bilmek önemlidir. Ayrıca genetik olarak sınıflandırılması (monojenik, kompleks), örnek yayılım (örneğin kistik fibrozis, orak hücreli anemi) ve temel genetik analiz yöntemleri (karyotip, PCR, dizileme) hakkında genel bilgi sahibi olunmalıdır. Genetik danışmanlık ve etik ilkelerdeki önemli bileşenlerin bileşenleri. lecture slides
2 Autism Spectrum Disorder
3 Crohn's Disease
4 Parkinson's Disease
5 Alzheimer's Disease
6 Spinal Muscular Atrophy
7 Turner Syndrome
8 Tay Sachs Disease
9 Down Syndrome
10 Klinefelter Syndrome
11 Cystic Fibrosis
12 Progeria Syndrome
13 Student Presentations

Recommended Optional Programme Components
Veri yok

Contribution of Learning Outcomes to Programme Outcomes
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10 P11 P12
C1 5 4 3 3 2 2 3 3 3 2
C2 5 3 3 2 2 3 3 3 3 2
C3 5 4 4 3 2 3 4 3 3 3

Contribution: 1: Very Slight 2:Slight 3:Moderate 4:Significant 5:Very Significant


https://sis.agu.edu.tr/oibs/bologna/progCourseDetails.aspx?curCourse=71986&lang=en